PRINCIPAL SCIENTIST, IMMUNOLOGY-LEAD EVALUATION AND CELLULAR PHARMACOLOGY

Johnson and Johnson is recruiting for a Principal Scientist, Immunology-Lead Evaluation and Cellular Pharmacology located in La Jolla, CA.
At Johnson & Johnson, we believe health is everything.
Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal.
Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.
Learn more at https://www.
nj.
om/.
The Lead Evaluation and Cellular Pharmacology team is a part of the Discovery Technologies and Molecular Pharmacology (DTMP) organization, a critical group in the larger Therapeutics Discovery (TD) organization.
We are committed to the delivery of high-quality chemical leads and clinical compounds in all Therapeutic Area discovery teams.
Specifically, this position requires deep scientific and technology expertise in multiple fields including immunology, cell biology, pharmacology, screening assay development and execution, with an ability to work collaboratively with internal partners and collaborators.
Key Responsibilities.
Work closely with immunology disease area biologists and chemists, to propose, initiate and complete fit-for-purpose assays that advances the programs.
Conceive of and implement hit finding plans for early-stage programs in collaboration with therapeutic area partners and multidisciplinary DTMP teams.
Exhibit an awareness of new technological advances and scientific knowledge in the field and apply these to high-throughput (HT) cellular assays.
Propose and oversee instrument acquisition and skill training towards building innovative technology platforms.
Supervise writing and execution of SOPs and troubleshooting of the assays in support of medicinal chemistry efforts, assuring high-quality data analysis and timely reporting.
Contribute data and methods to compelling scientific presentations and reports for internal review meetings and scientific journals/professional conferences.
Qualifications Education.
Ph.
.
in Immunology, Cell Biology, Biochemistry, or related fields, with a minimum of 6 years of industry experience is required, preferably in a drug discovery setting.
Experience and Skills.
Required.
Knowledge of immune cell signaling pathways and disorders is required.
Experience with methods of modulating disease state with pharmaceutical agents is required.
Demonstrated success in project leadership bringing together a multidisciplinary team and advance programs to gated stages is required.
Experience interpreting results in the context of Structure Activity Relationship (SAR) is required.
Solid understanding of Research Operating Plan (ROP) and ability to design fit-for-purpose SAR and MOA assays is required.
Hands-on experience in the establishment of robust miniaturized cell-based assays is required.
Operation and efficiency driven mentality that enables building end-to-end processes is required.
Deep understanding of trouble shooting and quality control (QC) of medium to high-throughput assays is required.
Demonstrated excellence in both written and verbal communication is required.
Ability to build collaborative working relationships is a must.
Preferred.
Experience managing early drug discovery programs for immunological disorders is preferred.
Experience working with laboratory automation and high-throughput screening is preferred.
The anticipated base pay range for this position is $ to $.
The Company maintains highly competitive, performance-based compensation programs.
Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan.
The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation’s performance over a calendar/performance year.
Bonuses are awarded at the Company’s discretion on an individual basis.
Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs.
medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.
Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k).
Employees are eligible for the following time off benefits.
Vacation – up to 120 hours per calendar year.
Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington – up to 56 hours per calendar year.
Holiday pay, including Floating Holidays – up to 13 days per calendar year.
Work, Personal and Family Time - up to 40 hours per calendar year.
Additional information can be found through the link below.
For additional general information on Company benefits, please go to.
https://www.
areers.
nj.
om/employee-benefits.
This job posting is anticipated to close on .
The Company may however extend this time-period, in which case the posting will remain available on https://www.
areers.
nj.
om to accept additional applications.
Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit www.
areers.
nj.
om.